Currently, the main treatment methods for choledocholithiasis include general treatment, medication and surgery, but the specific efficacy varies from person to person, and it is impossible to say which one is the best. 1. General treatment: It is the main symptomatic treatment for asymptomatic people and people who cannot have surgery for the time being. It includes light diet, nutritional support, physical cooling and so on. 2. Drug therapy: mainly as an adjuvant therapy or preoperative preparatory therapy, according to the presence of symptoms for the choice of medication. Commonly used drugs are ① anti-infective drugs: such as ceftazidime, moxifloxacin, etc., mainly used for people with cholangitis; ② antispasmodic and analgesic drugs: such as diclofenac sodium, ibuprofen, etc., for people with episodes of biliary colic. 3. Surgery: the most important method of treating this disease. Commonly used surgical procedures include choledochotomy and lithotripsy, endoscopic retrograde cholangiopancreatography and so on. However, it should be noted that the scope of application of the above treatments is different, and the therapeutic effect of different therapies may vary depending on the individual’s physical condition, severity of the disease and other factors, so there is no so-called “best” “most effective” treatment method applicable to all patients. Therefore, there is no “best” or “most effective” treatment for all patients. In summary, diagnosed choledocholithiasis, must be under the guidance of the doctor according to the actual situation of the individual treatment program development and adjustment, in order to strive for a good prognosis. Do not blindly dispose of them on your own to avoid inappropriate intervention and adverse consequences.