Heart failure is the leading cause of death in people over 60 years of age, with high morbidity and mortality despite the good results achieved with pharmacological treatment. Cardiac resynchronization therapy (CRT), a three-chamber pacemaker, can correct the delayed electrical excitation conduction and asynchronous mechanical activity of the failing heart by direct multi-point synchronous electrical pacing, achieve electro-mechanical resynchronization of the heart, reduce mitral regurgitation, increase cardiac output, improve the overall systolic and diastolic functions of the heart, and increase the efficiency of cardiac work, which is the biggest breakthrough in the treatment of refractory heart failure and the current hot spot of cardiac pacing therapy. This is the biggest breakthrough in the treatment of refractory heart failure and the current hot spot in cardiac pacing therapy. The patient was a 67-year-old patient with refractory heart failure who had suffered a large anterior wall myocardial infarction and the current application of various heart failure corrective drugs was not effective. The patient had an extremely enlarged left ventricle (78 mm), an extremely reduced ejection fraction (only 29%), and complete left bundle branch block. The patient’s condition was very serious, and he came to the Cardiology Department of the —- Baikouen International Peace Hospital. Director Ding Chao checked the room, carefully analyzed the patient’s condition, and faced with the patient’s and his family’s eager eyes and great desire to live, decided to give the patient the latest international technology for the treatment of intractable heart failure – the placement of a cardiac three-chamber pacemaker (CRT). After the operation, the patient’s chest tightness and shortness of breath were significantly relieved, and he felt comfortable all over, and he could sleep completely flat at night, and he no longer woke up at night as he used to.