Cracked corners of the mouth need to carefully observe the symptoms of the corners of the mouth, if simply just a crack, there is a slight pain you can choose to use 0.03% tacrolimus ointment applied to the cracked area, will soon make the corners of the mouth to return to normal. If there are no blisters on the fissure area, it is considered to be simple perioral dermatitis, you can choose to use vitamin E cream or urea ointment to apply, if the fissure area of the corner of the mouth appears dense small blisters, recurring periodically, it is considered to be herpes simplex, you can choose to use oral vaxilovir, together with topical recombinant human interferon alpha-2b gel or acyclovir ointment to carry on the treatment. Don’t eat chili peppers or foods that are too acidic or salty before the symptoms have fully recovered to prevent irritation to the wound site, which is not conducive to recovery.