With the increasing incidence of malignant tumors in China in recent years and the development and integration of modern medicine and traditional Chinese medicine, more and more patients with malignant tumors treated by surgical resection and radiotherapy are actively seeking treatment by Chinese medicine. As one of the valuable heritages of traditional Chinese medicine, the cream formula, which was popular in the upper-class society in ancient China, can play a unique role in improving patients’ constitution, tonifying deficiency and eliminating diseases, so it is of great significance to the treatment of malignant tumor patients. (1) Adhering to the principle of “treating with evidence” and attaching importance to the combination of evidence and disease: Chinese medicine treatment of tumor is not simply a pile of drugs, but also requires treating with evidence, following the method of cubing, and dispensing drugs according to the ruler, minister and adjuvant. Therefore, in actual application, we must identify the strength and weakness of the body’s qi, blood, yin and yang according to yin and yang, deficiency and reality, surface and internal, cold and heat, and clarify the direction of supplementation and elimination of evil, in order to restore the righteousness and eliminate evil. However, because of the unique characteristics of different tumor development process, biological behavior and the diversity of comprehensive treatment means, so on the basis of Chinese medicine identification, Western medicine identification should be considered at the same time to clarify the nature of the tumor and the focus of Chinese medicine in different periods of tumor treatment in order to achieve the ultimate curative effect. (2) While treating from “deficiency”, it is necessary to supplement with anti-cancer and detoxification products: Although cream formula is classified as a tonic product, but in actual application, it is not just a tonic method, “deficiency of positive cancer and internal gathering of toxins” is the basic etiology and pathogenesis of tumor. “Therefore, it is necessary to attack the evil at the right time and treat it according to the evidence. Therefore, it is necessary to attack the evil at the right time and treat it according to the evidence. Although helping the righteous is the root of tumor treatment, which can improve the patient’s constitution, replenish the qi and blood and get rid of the evil, the ultimate goal of tumor treatment is to get rid of the cancerous toxin, so the two complement each other and cannot be neglected. (3) Tonic can be taken in all seasons, but it is necessary to follow the rule of changing seasons: Although the onset of tumor does not have strict seasonal characteristics, because tumor patients have deficiency of vital energy, it is not necessary to stick to winter as the best time to take tonic. However, according to the characteristics of the disease, on the basis of supporting the righteousness to fight cancer and detoxify the toxin, and according to the season, we should use products to dispel wind in spring, clear heat and dampness in summer, moisten dry products in autumn, and warm yang medicine in winter, so that the tonic can be properly taken to achieve the purpose. (4) Combining with modern pharmacological research results, flexible selection of medicine and formula: Modern pharmacological research has confirmed that many Chinese medicines have anti-tumor effects, so reasonable anti-cancer drugs must be selected for treatment, for example, when supporting the righteousness, Ginseng, Astragalus, Poria, Atractylodes; when deficient in blood, Shu Di, Angelica, Bai Shao; when deficient in yin, chasteberry, dry lotus grass, asparagus; when deficient in yang, Eucommia, Baji Tian, etc. To dispel the evil: to clear heat and detoxify the toxin, there are Santalum album, Semen, Semen lotus, Phyllostachys alba, Vine pear root; to invigorate blood circulation and remove blood stasis, there are turtle worms, centipedes, scorpions, and spotted cucumber; to soften hardness and disperse knots, there are mountain cichlid mushrooms, Xia Ku Cao, seaweed, and kombu; to resolve phlegm, there are zhe Bei, Semen, Nan Xing, and soapberry, etc. And for identifying diseases: lung cancer: cat’s claw herb, mountain cichlid mushroom, fishy herb, zhebei; breast cancer: dandelion, perforated gynostemma, leaky reed; esophageal cancer: stone see-through, wei lingxian, gecko; stomach cancer: vine pear root, lobelia; liver cancer: earth turtle worm, pendula, mountain cichlid mushroom; colorectal cancer: coix seed, wormwood, mountain cichlid mushroom, ghost arrow feather, bitter ginseng, etc. (1) Post-operative patients with weak constitution: Due to the depletion of qi and blood during surgery, post-operative tumor patients are mostly suffering from deficiency of qi and blood, so the formula can not only benefit the qi and blood, regulate the spleen and stomach, but also take into account the “residual toxicity” to restore the patient’s constitution and clear the remaining cancer toxicity in the body. (2) Adverse reactions during radiotherapy: Besides surgery, chemotherapy and radiotherapy are also important means of treatment for malignant tumor patients, but radiotherapy can lead to nausea and vomiting, bone marrow suppression, impaired heart, liver and kidney function, neuropathy and other adverse reactions, which bring pain to tumor patients while undergoing treatment; moreover, many patients cannot tolerate radiotherapy due to poor physical quality and lose the opportunity of treatment. However, the efficacy of TCM cream can not only alleviate the adverse reactions of radiotherapy patients and complete radiotherapy successfully, but also regulate the physical quality of patients so that they have the opportunity to receive radiotherapy treatment; and it can also give full play to the anti-cancer effect with radiotherapy. (3) Stable condition to prevent tumor recurrence and metastasis For early stage tumor patients, surgery is the main treatment option, but because most patients do not need radiotherapy and other western medicine follow-up adjuvant treatment after surgery, patients are often afraid of tumor recurrence and metastasis, or some patients with stable condition who use Chinese medicine for comprehensive treatment and do not need short time to adjust prescriptions. Poultices are often a good choice, not only can they be taken for a long time, with less adverse effects and eliminate patients’ fears, but most importantly, they can be the most convenient and cheaper means to achieve the purpose of tumor treatment.