Postoperative infection of bone fracture may be muscle layer infection, osteomyelitis, etc., which is generally easier to treat, but osteomyelitis has a longer treatment time and is difficult to be cured. 1. Muscle layer infection: if only the incision area or superficial muscle infection occurs after surgery, it is easy to cure, and the bacterial type of infection can be determined through examination and appropriate anti-inflammatory and antibacterial treatment, such as dilating the wound, using antibiotics such as cephalosporin, levofloxacin and so on. 2. Osteomyelitis: If the infection is not controlled and develops into bone infection, it is called osteomyelitis. Once diagnosed, it is necessary to remove the infected tissue or necrotic bone through surgery in time, and use various kinds of sensitive antibiotics in combination, such as moxifloxacin, ceftriaxone sodium, etc., in order to eradicate the infection as soon as possible, to avoid the condition of prolonged healing or the emergence of a variety of complications. Patients with postoperative fracture infection need to be diagnosed by a doctor to determine the treatment plan, and actively cooperate with the doctor for treatment to avoid aggravation of the condition, resulting in difficult to cure. The use of the above drugs should be in accordance with medical advice.