Aspirin enteric tablets are recommended to be taken within 15-30 minutes after meals, not before meals because aspirin has digestive and gastrointestinal side effects, and common side effects can include nausea, vomiting, upper abdominal discomfort and pain. Oral aspirin enteric tablets can irritate the mucosa of the gastrointestinal tract and cause abdominal discomfort. Taking them on an empty stomach for a long time can also lead to damage to the mucosa of the gastrointestinal tract and induce patients to develop peptic bleeding and ulcers. For patients with a history of gastroduodenal ulcer or reflux esophagitis, they should not be taken before meals or on an empty stomach, but after meals. It is usually not recommended to take large amounts of aspirin enteric tablets for a long period of time. In case of serious upper gastrointestinal bleeding and other adverse reactions, it is important to go to the hospital quickly for medical consultation.