Skeletal deformities may involve the upper limbs bilaterally, with the left side being more severe. The radial carpal bones may be delayed by ossification so that the base of the first metacarpal is close to the midline, juxtaposed with other metacarpals, and the interphalangeal bone may disappear. There is no bone in the thumb but soft tissue. Common tests: 1. Doppler echocardiography There are many red blood cells within the blood, which reflect and scatter ultrasound and can be considered as a tiny source of sound. The probe is placed in the intercostal space without moving and emits ultrasound. When the red blood cells flow in the heart or large blood vessels, the sound frequency scattered by the red blood cells changes. 2.Cardiovascular angiography Cardiovascular angiography is the rapid injection of contrast agent into the heart cavity or blood vessels through the heart catheter, so that the heart and blood vessel cavities are visualized under X-ray irradiation, and at the same time, there are methods such as rapid film, television photography or tape recording to film the visualization process of the heart and blood vessel cavities, and from the results of the visualization, we can see the sequence of blood flow containing contrast agent, as well as the filling of heart vessels, so as to understand the physiological and anatomical changes of the heart and blood vessels. It is a valuable method to diagnose the heart and blood vessels. It is a valuable method to diagnose cardiovascular diseases. Doppler echocardiography can be used to analyze the thickness of the heart wall, the speed, amplitude, slope and trajectory of the valves and other high-speed movements, the direction of blood flow, and the nature of blood flow. 4.Chest fluoroscopy Fluoroscopy is a direct examination where the patient is placed between the X-ray tube and the fluorescent screen. It can do comprehensive dynamic direct observation, such as heartbeat, transverse septal activity, gastrointestinal motility, joint activity, etc. 5.Chest plain film Chest plain film, also called chest radiography. The X-ray image obtained from radiography is much clearer than that from fluoroscopy. Its advantages include: (1) the image of the examined area is permanently preserved on the film, which can be used for analysis, discussion and review and control; (2) it can be preserved as scientific research data; (3) radiography can show the microstructure, such as the early source of disease above 2mm is clearer than fluoroscopy. (4) radiographs can examine thicker parts of the body and enable patients to receive less X-rays. 6.Computer three-dimensional reconstruction technology Computer three-dimensional reconstruction technology has important significance in simulating the pelvis, determining the scope of malignant tumor resection and individualized design of prosthesis. 7.CT examination of the chest CT examination of the chest is a method of examining the chest by X-ray computerized tomography (CT). 8.White blood cell count White blood cell count refers to counting the number of white blood cells contained in a unit volume of blood. It was formerly known as white blood cells and is an important part of the body’s defense system. 9.Two-dimensional echocardiography is a basic examination method that can clearly, visually and in real time show the morphology, spatial location and continuous relationship of each structure of the heart. 10.Transesophageal echocardiography (TEE) is a new window for cardiac macrovascular imaging by using a special exploration position and high-quality image display, which expands the scope of transthoracic ultrasound examination and makes up for the shortcomings of TEE, thus gradually becoming more widely used in clinical practice.