(Disclaimer: This article is for scientific purposes only, in order to protect the patient’s privacy, the relevant information in the following content has been processed) Abstract: The patient in this case, self-reported pain in a fixed position in the knee joint, with the feeling of playing a soft leg, and took medication on his own during the period of pain with no significant relief and then consulted the doctor. After admission, the examination found that the floating patella test was positive, the grinding test was positive, followed by the knee joint frontal and lateral X-rays and MRI examination, the results showed chondromalacia of the patella. The patient was given medication + rehabilitation exercise, and after treatment, the symptoms were relieved, the condition was obviously controlled, and the chondromalacia was reduced. Basic information】Female, 40 years old 【Disease type】 Chondromalacia patella 【Hospital】 Hunan Brain Hospital 【Date of consultation】May 2022 【Treatment plan】Medication (Celecoxib capsule+Bicuculline capsule+Glucosamine Sulfate tablets+Mai Zhi Ling tablets)】+Rehabilitation exercise (Knee extension and straight leg raising+Static squatting against the wall)】 【Treatment period】Outpatient treatment for 1 month, 1 month later for review 【Treatment effect】Symptoms relieved, condition obviously under control. Effectiveness] Symptoms relieved, condition under control, cartilage softening reduced I. Initial Consultation One day in May 2022, a middle-aged female patient was seen in the outpatient clinic, who complained of pain in the fixed position of the knee joint 4 months ago without any obvious cause, and felt a dull ache in the knee joint when she sat for a long time, and felt a friction sensation when going up and down the stairs, accompanied by the sensation of a limp leg. 1 week ago, there was a swollen and painful left knee joint, which was treated with Huangdao Yihuoluo (黄道益活络) tablet on its own. The swelling and pain in the left knee joint appeared 1 week ago, and the patient came to the hospital after no significant improvement with the external application of Huangdao Yi vitalizing oil. After examination, he was found to have a positive patellar grinding test and a positive floating patella test, and was advised to undergo a detailed examination. After careful inquiry, the patient was told that he liked to kneel and wipe the floor with his hands, had a patellar dislocation when he was young, lived in a staircase house, and often carried heavy objects up and down the stairs. Considering the patient’s medical history, the patient’s knee was then examined, such as the knee joint frontal and lateral X-ray and MRI, and the results showed that there was degenerative change in the patellar articular cartilage, and patellar cartilage chondromalacia should be taken into account. Therefore, the patient was advised to take conservative treatment, i.e. anti-inflammatory and analgesic drugs, celecoxib capsule + bisacodyl ryanin capsule orally; glucosamine sulfate tablets orally; mazolin tablets orally to reduce the swelling. At the same time, rehabilitation exercises are carried out to improve the quadriceps muscle strength, such as knee extension and straight leg raising, squatting against the wall. It should be noted that during the rehabilitation exercise, the knee joint should be protected, such as wearing protective gear, and the patient should avoid deep squatting. Third, the effect of treatment After the patient through the drug with rehabilitation exercise treatment, the effect is remarkable, before the consultation of the knee pain, swelling, exertion of the leg when playing soft and other symptoms have improved significantly. After 1 month of treatment, the pain and swelling had completely subsided, showing that the patient’s condition had been obviously controlled, and the examination found that the floating patella test and grinding test had turned negative, and the MRI results suggested that the chondromalacia of the patella had been reduced. Fourth, notes The patient in this case through active and effective treatment, the symptoms disappeared, can work and live a normal life, sincerely feel happy for it. Since the patient is an outpatient, lack of medical staff supervision, so consciously observe their own situation is particularly important, the patient is advised that whether it is during the period of treatment or consolidation of treatment, should be timed to quantitative medication, to avoid stopping medication, resulting in recurrence of the disease, but also consciously comply with the doctor’s instructions to follow the follow-up appointment on time. When you are at home, you still need to insist on rehabilitation exercise, and during the rehabilitation exercise, you should wear a knee brace and avoid doing deep squatting and other movements. In daily life, avoid weight bearing on the knee joint, such as frequent squatting and lifting heavy objects up and down stairs. Fifth, personal feelings Clinical chondromalacia patella is not uncommon in patients, often in the early symptoms did not pay attention to the patient more than their own external use of some drugs, resulting in symptoms are getting worse and worse. Especially for young and middle-aged patients, if the knee symptoms, should focus on asking whether there is a bad work life habits, knee symptoms in what circumstances aggravated. In addition, it also needs to be identified with osteoarthritis and rheumatoid arthritis. Patients with chondromalacia patella often have obvious discomfort or stiffness in the knee joint at rest as the patient in the case, and they usually need to improve their joint activities at an early stage, carry out activities to protect their knee joints, or take medication for nutrition of cartilage, and if the symptoms are obvious, they should actively consult a doctor to carry out checkups and treatments, just as the patient in the case.