The cause of lobular tumors of the breast is not clear, but is generally thought to be related to endocrine and fibrous tumors, which require surgical treatment. Lobular tumors of the breast are tumors of mixed epithelial and mesenchymal origin, which can be benign, junctional or malignant, and are rare. The etiology of lobular tumors is currently unknown. Lobular tumors are highly prevalent in women aged 40-50 years, and are rare in adolescent and pre-pubertal, male lobular tumors, so lobular tumors may be related to endocrine disorders in perimenopausal women. Some studies suggest that the occurrence of lobular tumors is related to fibrous tumors. It has been suggested that lobular tumors develop from fibromas, and that the epithelial component of breast fibromas may progress to breast cancer, while the mesenchymal component may develop into lobular tumors. In addition, the development of lobular tumors may also be related to race and geography. It is recommended that those with lobular tumors of the breast seek prompt medical attention, which usually requires surgical treatment with wide local excision.