1.Older people over 60 years old, regardless of male or female and whether they are obese or not. 2, obese middle-aged men and post-menopausal women. 3.Patients with hypertension, atherosclerosis, coronary heart disease, cerebrovascular disease (such as cerebral infarction, cerebral hemorrhage). 4.Diabetes mellitus (mainly type II diabetes). 5.Arthritis of unknown cause, especially in middle-aged or older patients, characterized by the onset of monoarthritis. 6.Kidney stones, especially patients with multiple kidney stones and bilateral kidney stones. 7, members with a family history of gout. 8.People of middle age or older who have a long-term taste for meat and have a habit of drinking alcohol. Anyone who belongs to any of the above listed conditions should take the initiative to go to the hospital for laboratory tests on gout to detect hyperuricemia and gout as early as possible, and not wait until typical clinical symptoms (such as subcutaneous gout stones) have appeared before seeking medical attention. If the blood uric acid is normal at the first examination, the possibility of gout and hyperuricemia cannot be easily excluded. It should be reviewed regularly in the future, at least once a year for a health check. This can lead to a much higher rate of early detection of gout. In case of gout and corresponding complications, timely consultation at the Department of Nephrology and Rheumatology is recommended.