The Beijing Biological and Kexing neocoronavirus vaccines, which belong to different manufacturers and are inactivated neocoronavirus vaccines of the same technical route, can be mixed for vaccination. According to the current vaccination guidelines, it is recommended to prioritize the use of vaccines of the same type and from the same manufacturer to complete the whole process of vaccination in order not to affect the immunity effect of vaccination. However, it is possible to mix vaccines from other manufacturers when there is a shortage and the supply of vaccines cannot be continued, or when the vaccinators are in different locations. Since both vaccines are inactivated vaccines, the principle is to retain the antigenic components of the virus and induce the body to produce immune antibodies. Therefore, at the time of vaccination, it is important to inform the on-site medical professional of the manufacturer and type of the first dose of vaccine, as well as past medical and allergy history. It is up to the medical professional to determine the type and manufacturer of the vaccine to be administered.