Hand sweating, a condition in which excessive secretion of sweat glands is caused by sympathetic nerve over-excitation. The sympathetic nerve governs sweating throughout the body. Normally the sympathetic nerves regulate the body’s temperature by controlling sweating. In hyperhidrosis, however, sweating is completely out of control. The disease is hereditary in 12% of the population. It is a congenital disorder. Most people develop hand sweating from childhood and it gets worse in adolescence. Patients with hyperhidrosis are healthy and normal except for sweaty hands. However, the symptoms often cause problems in school, work or social life and require medical treatment. Whether it’s hot in the summer or cold in the winter, people with hyperhidrosis tend to have wet palms most of the time, and prolonged wet hands often cause easy peeling, which is even more unsightly. School-age youth often due to excessive hand sweat will be wet exam paper and affect the examination, often the test paper is not written on the already wet. Teenagers are afraid to hold hands with others, and even shaking hands is a problem. In severe cases, the palms of the hands may even show signs of eczema dermatitis. As adults, it also causes inconvenience in their work and social activities. The patient’s self-confidence is seriously affected. Hyperhidrosis patients often combined with the phenomenon of sweaty hands and feet, and the patient’s sweat usually does not have an odor. Clinical symptoms of hand sweating can be graded, for example, the degree of hand sweating disease from mild to severe divided into three levels: mild for the palm of the hand wet; moderate for the palm of the hand sweating wet a handkerchief; severe for the palm of the hand sweating in the form of beads of drops. If most of the following characteristics are met: juvenile onset, family history, sweating is bilateral symmetry, triggering factors for emotion, exercise, high temperature, etc.; sleep without sweating, most of them are considered as hyperhidrosis. Hand sweating treatment: minimally invasive thoracic sympathetic trunk amputation, only need to cut in each side of the axilla 1 diameter 1.5 cm tiny incision, not open chest, the operation process only takes less than half an hour, its incision is tiny, pain is small, scar small does not affect the aesthetic, usually about 1 day after the operation discharged from the hospital, the vast majority of patients immediately disappear after the operation symptoms. High cure rate and quick return to normal working life. Patients’ pain of several years or decades disappears immediately, and patients’ self-confidence increases rapidly, and they can soon dissolve into normal social life, interpersonal communication and work. Psychometric studies have found that there is also a significant improvement in the mental health of patients after surgery. The success rate of the treatment is as high as 95-99%.