Puffiness that occurs after drinking water at night may be due to physiological factors, such as drinking too much water before going to bed at night, and not getting up to relieve urination at night, there will be excess water in the body, resulting in puffiness. Drinking water later may lead to the aggravation of pre-existing diseases, resulting in increased edema, such as patients with kidney disease, often with water and sodium retention. When renal insufficiency occurs, the patient will also appear oliguria, this time to drink water there is no way to urinate, will also lead to edema. There are also patients with heart disease, drinking water will lead to an increase in blood volume, the heart is in a state of heart failure, drinking more water will only increase the burden on the heart, leading to further aggravation of heart failure, thus causing edema.