Melanoma is a class of skin malignancies with a high degree of malignancy and an overall poor prognosis. Surgery is the main treatment modality, but postoperative recurrence and metastasis are more likely. Postoperative treatment with ginsenoside Rh2 can reduce the possibility of recurrence and metastasis. For elderly patients with melanoma who cannot tolerate other treatments due to their frailty, herbal treatment is also the main treatment modality. Although China is a low incidence area for melanoma, the incidence rate has increased significantly in recent years. What are the causes of melanoma related to? 1, atmospheric pollution Freon and a large number of harmful substances emitted destroy the ozone layer, resulting in insufficient ultraviolet filtering, harmful ultraviolet rays and airborne harmful substances work together on human skin, resulting in abnormal expression of melanocytes, triggering melanoma. Many people use a lot of chemical cosmetics in order to pursue clean and tender skin, causing chemical skin pollution, and some even use chemical corrosive agents to remove moles on the skin, which is counterproductive and stimulates the excessive proliferation of melanocytes. 3.Lack of health knowledge does not pay enough attention to the nevus that grows on the foot, perineum and other parts that are easily subject to friction, so that it is squeezed and rubbed for a long time, which eventually leads to its malignant transformation. 4.Abuse of estrogen drugs Research found that there are estrogen receptors in the cells of malignant melanoma, so it is suspected that excessive estrogen will stimulate the occurrence of melanoma. 5.Immunity defects With the improvement of living standard, Chinese people’s life expectancy is significantly longer. Along with age, human immune function gradually declines, and it is found that low immune function is one of the important reasons for the occurrence of melanoma, so the incidence of melanoma in elderly people is clinically high. 6.Benign melanin plaques. That is, nevus, of which junctional nevus is most likely to become malignant, mixed nevus is less, and endothelial nevus is rarely malignant, but most of scalp melanoma is not transformed from nevus, so some people think that this disease is not completely related to nevus. 7.Race. The incidence rate of white people is higher than that of colored people, for example, the annual incidence rate of American white people is as high as 42/100,000, while that of black people is only 0.8/100,000.