For whether insulin needs to be injected for a long time, it is decided according to the function of the pancreas, liver and kidney. In case of type 1 diabetes, where the pancreatic secretion of insulin is absolutely insufficient, lifelong application of insulin is required to lower blood sugar. In the case of patients with moderate or above abnormal liver and kidney function, oral hypoglycemic drugs will increase the burden on the liver and kidneys, and long-term application of insulin is also recommended. Patients with type 2 diabetes with normal or mildly impaired liver and kidney function can choose oral hypoglycemic drugs or insulin combined with oral hypoglycemic drugs for glucose-lowering treatment. When blood glucose is high, insulin can be applied briefly for intensive glucose-lowering, and after blood glucose drops, it can be changed to oral hypoglycemic drugs. Some patients with first-onset type 2 diabetes may enter the honeymoon period after a period of intensive insulin glucose-lowering, and can achieve blood glucose control standards without the use of drugs or insulin, simply through diet and exercise control.