In fact, there are many causes of pain and itching during pregnancy, so let’s find the causes together and find ways to deal with itching during pregnancy. Pregnancy itch is the itching that often occurs during a woman’s pregnancy. Throughout pregnancy, a pregnant woman’s skin may seem particularly sensitive due to increased hormones. Symptoms such as itchy skin and itchy vulva can occur, which can be severe enough to interfere with work and rest. There is a specific type of pruritus called intrahepatic cholestasis during pregnancy, which occurs in about 0.7% of cases and is most often seen after 32 weeks of gestation. It has no significant adverse effects on the mother, but is a cause of perinatal mortality and its risk to the fetus has always been of concern to clinicians. Pruritus during pregnancy often begins in the abdomen, such as with the enlargement of the pregnant uterus, the skin of the abdominal wall of the pregnant woman mostly appears purple or light red stretch marks and itching. The skin rash, the degree of itching varies, the lighter the skin is only slightly itchy, the heavier the itch is unbearable, restless, sleepless at night, painful, some even scratch the skin to temporarily stop itching, resulting in the whole body scratches, but also prone to skin septic infection. The symptoms of pruritus are mainly on the palms of the hands, feet and extremities, with varying degrees of severity, without a rash, and often accompanied by mild diarrhea and even jaundice. What kind of treatment is available for different causes? What should I do in my daily life? Itchy skin should be avoided as much as possible. Generally, the itching can be reduced by gently massaging the skin or scrubbing with warm water. Also mint water and aloe vera water can relieve some of the symptoms. Severe cases can try topical application of stove glycolic lotion. Some itching is caused by allergies, such as taking certain drugs or contact with allergic substances, as well as climate change, etc. Most occur on exposed skin, or a rash appears all over the body or locally. As long as the allergens are removed and some anti-allergy drugs are used locally, the itching can be relieved and disappear. In addition, mold or trichomonas, some chemical stimulation, poor hygiene habits such as wearing non-breathable chemical fiber underwear, etc., can also induce itching in the vulva during pregnancy, such itching as long as you find the cause, symptomatic treatment, the symptoms will soon be eliminated. The mother-to-be should not wear non-breathable, tight-fitting clothes in daily life. You should try to loose, breathable, easy to absorb sweat, material to cotton is better, and avoid being in a humid and hot environment. Do your best to protect yourself from the sun and avoid taking too many baths and high water temperatures every day, as this will aggravate the itching. Avoid taking baths and hot springs. Avoid using too many cleaning products when taking a bath, and rub some lotion to moisturize afterwards. Prevent the stimulation of food factors, such as eating less chili, ginger, raw garlic and other irritating foods. Seafood intake should be moderate, because seafood can aggravate the itchy skin. However, itchy skin without a rash should be taken seriously and should not be considered as “fetal gas”, but should be told to the obstetrician immediately to rule out intrahepatic cholestasis during pregnancy. In the case of ICP, it is important to pay attention to the fetal movement count to detect signs of fetal hypoxia in a timely manner. There are significant geographic and racial differences in incidence. The etiology of the disease is unknown and genetic, environmental and endocrine factors all play a role. It can occur at any gestational week and gestation, often in mid to late gestation, and is characterized by pruritus and abnormal biochemical parameters such as bile acids. It is classified as a high-risk pregnancy because it mainly endangers the perinatal infant and the mother is at increased risk of postpartum hemorrhage. The diagnosis is an exclusionary diagnosis of the disease, therefore other diseases causing abnormal liver function should be excluded when making the diagnosis of ICP. Screening for all types of viral hepatitis, herpes virus, cytomegalovirus, and liver ultrasound should be performed prior to confirming the diagnosis. Mild ICP: Outpatient treatment is the mainstay until 37 weeks and consists mainly of intensive fetal monitoring and oral medication. Observation until full term and vaginal trial of labor under close supervision. For those who are not in labor beyond the due date, even small doses of intravenous contractions can be considered to induce contractions, but the indications for cesarean delivery can be relaxed appropriately. Severe ICP: immediate hospitalization, active treatment, close monitoring of the fetus, cesarean section around 36 weeks to terminate the pregnancy. However, it is important to note that evidence-based medicine proves that no monitoring method (ultrasound, fetal monitoring, biochemical indicators) can predict or avoid sudden fetal death in ICP.