Azoospermia may be caused by endocrine factors, abnormalities of the vas deferens, congenital testicular abnormalities or trauma to the testes, etc. Hormone therapy, intervention therapy and surgery are the main treatments. 1. Endocrine factors: If azoospermia is caused by endocrine factors, the hormone level in the body is disturbed, resulting in a decrease in sperm count, hormone therapy can be intervened under the guidance of doctors, such as injection of human chorionic gonadotropin. 2. Abnormalities of the vas deferens: If azoospermia is caused by abnormalities of the vas deferens, it is commonly caused by infections of the reproductive tract, resulting in the blockage of the vas deferens, which can be treated by surgical procedures, such as vasectomy, together with the treatment of anti-infective medications, such as levofloxacin, norfloxacin, and so on. 3. Congenital testicular abnormality: If azoospermia is caused by congenital testicular abnormality, it can be treated with estrogen injection, such as estradiol valerate injection, in combination with the doctor’s therapeutic advice. 4. Trauma: If testicular trauma leads to azoospermia, you can take anti-infective drugs, such as amoxicillin and levofloxacin under the guidance of a doctor. If the effect of drug treatment is not good, you can do vesicoscopic surgery. Once the examination found to have azoospermia, it is recommended to cooperate with professional urologists to improve the next step of the examination, such as routine semen examination, ultrasound of the urinary system and MRI of the seminal vesicles, etc., so as to clarify the cause of the disease, standardize the treatment in time and promote the recovery of the reproductive function.