There are many surgical approaches to the treatment of herniated discs in pain medicine, including chemical lysis, physical lysis, and physical extraction. Specifically, collagenase lysis is the representative procedure for chemical lysis; laser, radiofrequency, and plasma are progressive physical lysis procedures; and interventional intradiscal decompression, spinotomy, and foraminoscopy are progressive physical removal procedures. In addition, ozone injection is a method to improve the local lesion by stimulating its own function, and has been widely used in the outpatient treatment of lumbar spine lesions because of its great safety, simple operation, repeatable treatment, and non-toxic side effects.