The overproduction of adrenal hormones leads to an increase in glucocorticoids and hydrocorticoids, in addition to an increase in medullary secretion of catecholamines. First, due to the increase of glucocorticoids, will cause sugar, protein and fat metabolism disorders, which will cause the patient to show centripetal obesity, hypoproteinemia and blood glucose significantly increased. In addition, it will also lead to decreased resistance, easy to infection, also prone to osteoporosis, may lead to obvious bone pain and so on. Secondly, hypercorticism can lead to hypertension, hypokalemia, and in severe cases, periodic paralysis or even respiratory failure. Long-term increase in salt cortex can also affect renal function, and hypokalemia often leads to cardiac arrhythmia and prolongation of the QT interval. Third, catechol if increased often lead to palpitations, chest tightness and so on, leading to rapid type of arrhythmia, some patients will also have high blood pressure and so on.