Sequestering antibodies are a class of IgG-type antibodies produced by stimulation of the maternal immune system by human leukocyte antigens, trophoblast and lymphocyte cross-reacting antigens (TLX). It is believed that APLA in the blood of pregnant women can exhibit the following effects: 1. APLA neutralizes the alloantigen without rejection of the fetus; 2. Antibodies act directly on immunocompetent cells such as:CTL cells, NK cells, etc.; 3. Binds directly to antigens of the target cells, thus decreasing their sensitivity to immune responses involving the receptor cells. Previous studies have suggested that the occurrence of recurrent spontaneous abortion is related to the lack of APLA in the mother, and the higher the number of abortions, the higher the possibility of APLA deficiency in the body of the patient. insufficient production of APLA, the mother to the fetus produces a strong rejection of the phenomenon, which occurs in the early stages of pregnancy can be recurrent spontaneous abortion, and in the late stages of pregnancy, can be hypertensive disorders of pregnancy, intrauterine growth restriction of the fetus, or even intrauterine foetal death. Therefore, it is very necessary to perform APLA test for patients with recurrent spontaneous abortion. According to domestic and international experience, patients with recurrent spontaneous abortion should be tested for APLA first, and if APLA is negative, active immunotherapy with husband’s lymphocytes will be used. The specific course of treatment is 3-4 times of injection therapy before pregnancy, rechecking APLA, if APLA turns positive, conception can be planned (including ovulation monitoring, ovulation promotion, artificial insemination, in vitro fertilization, etc.), if APLA is still negative, it is necessary to continue the injection therapy until APLA turns positive before considering conception, and strengthening the injection therapy for 3 times after pregnancy. Numerous studies have confirmed that lymphocyte immunotherapy for RSA is effective and safe, and that APLA has a good prognostic value for the outcome of another pregnancy. Treatment Methods Medical personnel draw a certain amount of peripheral blood from the husband’s body for centrifugal precipitator lymphocyte isolation, culture, and then infuse back into the wife’s forearm skin. Commonly used measures: women are immunized 2-4 times before pregnancy, each time at an interval of 2-4 weeks, and women are reinforced with immunization 1-3 times around the 6th week of pregnancy. This is done until after the fourth or fifth month of pregnancy to ensure that the wife has a normal pregnancy!