Fosamax is the trade name, the generic name of the drug is alendronate, the difference between domestic and imported includes different drug prices, different manufacturers, different drug specifications, etc., but the efficacy of the drug role is not much obvious difference. The drug is divided into domestic and imported, of which the price of imported drugs is significantly higher than that of domestic drugs. Moreover, the manufacturers of domestic and imported drugs are different, so there is a certain difference in the processing technology of the drug. The dosage forms of domestic and imported drugs are also different. Domestic drugs are mainly low-dose and need to be taken daily. Imported drugs include low-dose daily dosage forms and high-dose weekly dosage forms. This drug is mainly used for the treatment of menopausal women with osteoporosis, the prevention of osteoporosis-induced fractures, and the treatment of osteoporosis in men. The use of this drug may produce side effects such as abdominal distension, abdominal pain, skin rashes, etc. It is contraindicated for pregnant women, children, lactating women or those who are allergic to the drug. The drug needs to be used under professional medical supervision.