Thigh pain should first be identified and then treated for the cause. Thigh pain may be caused by trauma, vascular disease, potassium deficiency, etc. If the cause of thigh pain is clearly potassium deficiency, it should be treated with potassium supplementation under the guidance of a doctor. If it is clear that the leg pain is caused by potassium deficiency, it should be treated with potassium supplementation under the supervision of a doctor and the treatment should be tailored to the cause of the pain. Thigh pain caused by potassium deficiency may be hypokalemic periodic paralysis, first of all, need to actively replenish potassium, if the blood potassium level >3mmol/L, can increase the food potassium intake and remove the causes of hypokalemia, usually high potassium foods are bananas, oranges and potatoes. Drugs to supplement potassium can be taken orally such as potassium chloride extended-release tablets, potassium chloride injection and potassium citrate oral solution. Potassium deficiency and thigh pain should be treated by an endocrinologist under the guidance of a doctor.