The location of Barrett’s esophagus is commonly found in the lower part of the esophagus. Barrett’s esophagus refers to a pathological manifestation in which the squamous epithelium of the lower esophagus is replaced by columnar epithelium in the gastrointestinal tract and other parts of the esophagus, which may have a tendency to become cancerous, so regular review is necessary to avoid disease progression. Barrett’s esophagus is usually seen as a result of gastroesophageal reflux disease (GERD) injury, and may present with symptoms such as heartburn, acid reflux, and discomfort in swallowing, etc. Diagnosis can usually be made by gastroscopy and pathologic examination. It is important to note that when diagnosed with Barrett’s esophagus, a suitable treatment plan should be chosen under the guidance of a doctor according to the specific condition, and regular review should be paid attention to in order to avoid the occurrence of cancer.