Is lupus nephritis type V still serious when it’s under control?

Whether lupus nephritis type V is serious or not when the disease is under control is assessed according to the clinical manifestations of the patient after treatment, the presence or absence of central nervous and cardiac involvement, and if there are no other extra-renal manifestations, it is relatively not considered to be serious. Lupus nephritis type V is called membranous lupus nephritis. The prognosis of patients with this type varies widely. Pathologic manifestations include diffuse thickening of the glomerular capillary basement membrane on light microscopy, with peg-like changes in the later stages, often accompanied by a certain degree of thylakoid hyperplasia and an increase in extracellular matrix, which is an important feature of membranous lupus nephritis nephropathy. Fibrosis occurs in the kidney after the damage of renal intrinsic cells, and the normal renal units with filtration function are replaced by fibrous tissues, losing the detoxification function, so that the toxin accumulates in the body and cannot be discharged out of the body. After lupus nephritis is under control, if there is no other extra-renal manifestation, it is not serious, but you still need to go to the hospital for regular checkups, maintain a healthy lifestyle and pay attention to your diet.