Trimethoprim, or trimethoprim maleate, is not recommended for long-term use and should be used in accordance with medical advice. Trimethoprim maleate has the effect of regulating gastric motility, terminal emetic, etc. It can be used to improve nausea, vomiting, loss of appetite, abdominal pain, diarrhea, abdominal distension, abdominal ringing, constipation and other symptoms caused by gastrointestinal motility dysfunction, as well as irritable bowel syndrome. However, adverse reactions such as constipation, bowel sounds, diarrhea, numbness in the mouth, abnormal liver function, vertigo, headache, and drowsiness can be seen with this medication, so long-term use is not recommended. The drug is contraindicated for those who are allergic to Trimethoprim maleate, and a clear diagnosis is required before using the drug for treatment, and other organic and occupational digestive diseases should be used with caution. Patients with skin rashes during use should stop the drug for observation. The drug should be used rationally under the guidance of a doctor to avoid adverse consequences.