Gonococcal smear did not see gram-negative diplococcus, indicating that the possibility of gonococcal infection is unlikely, but gonococcal infection can not be completely excluded. Gonococcal infection is a sexually transmitted disease, which develops after an incubation period ranging from 2 to 7 days after infection, and manifests itself in men as symptoms of urethral pus, painful urination, burning, and itching of the urethra; and in women as symptoms of cervical engorgement, edema, purulent discharge, itching, and irritation of the urethra. Gonorrhea can be diagnosed according to the history of unclean sexual intercourse, combined with laboratory tests. Gram-negative diplococci are not seen in the gonococcal smear, gonorrhea cannot be excluded, and secretion culture is needed after the incubation period, and Neisseria gonorrhoeae can be diagnosed as gonorrhea if it is found. Gonorrhea is usually treated with ceftriaxone and macrolide, which can be completely eradicated and will not recur after treatment without sequelae. Gonococcal smear did not see gram-negative diplococci, it is recommended that further medical examination to clarify the diagnosis.