Liquid nitrogen freezing large blisters will heal on their own without breaking, it is best not to break it on your own, usually in 2-3 days time will be self-absorption, self-pick may occur infection. It is normal to see large blisters after liquid nitrogen freezing, so pay attention to the size of the blisters. If the blisters are particularly small, they usually do not need to be treated and can be absorbed by the body on their own. If the blisters are too large to be absorbed on their own, you can choose to puncture them, but be sure to sterilize them and avoid getting them wet after puncturing them to prevent infection. The scab will fall off on its own in 7-15 days after picking, but don’t pick it with your hands after the scab, as infection can easily occur if it is not handled properly. Generally after the liquid nitrogen freezing will appear blisters, before the blisters do not disappear completely, must pay attention to protection, avoid touching the water to prevent infection.