The common causative organism is Staphylococcus aureus. Abscesses can originate from acute purulent infections or from the transfer of pathogenic bacteria from distant primary sources of infection via the bloodstream or lymphatic vessels. It is often due to necrosis and lysis of the inflamed tissue by the action of toxins or enzymes produced by bacteria, resulting in the formation of a pus cavity in which the exudate, necrotic tissue, pus cells and bacteria together make up the pus. The fibrin in the pus forms a reticulated scaffold that restricts the lesion to a localized area, with congestion and edema and leukocyte infiltration around the other pus cavity. The final formation of the wall of the abscess cavity is dominated by the proliferation of granulation tissue. Abscesses can present with different clinical manifestations depending on their location. Acute bacterial endocarditis is often caused by pathogenic bacteria, with Staphylococcus aureus, Streptococcus haemolyticus, Streptococcus pneumoniae, S. influenzae, S. pyogenes, and E. coli being the most common. These bacteria are more virulent, have a rapid onset, are severe, and are often secondary to infections at other sites as part of a systemic infection, such as meningitis, pneumonia, and thrombophlebitis, sometimes accompanied by metastatic septic lesions in other organs. It usually occurs in the normal heart. The prognosis of this disease depends on the early or late treatment, the ability of antibiotics to control the primary bacteria, the degree of damage to the heart valves and the patient’s resistance. Staphylococcus aureus, hemolytic streptococcus, diplococcus pneumoniae, gram-negative bacilli, etc., can damage the infected valve leaflets more quickly due to the virulence of the bacteria, and if heart failure occurs during antibiotic treatment or if the original heart failure is aggravated, a new murmur or murmur is variable If there is embolism, etc., it is a sign that the infection cannot be controlled, and it is necessary to consider changing antibiotics. After strengthening the supportive therapy and improving the general condition, we should strive for early surgery. If the delay is too long, the condition may deteriorate progressively and the opportunity for surgery is often lost.