Unilateral tinnitus accompanied by hearing loss may be related to cerumen impaction, otitis media, neurodeafness and other diseases, which need to be treated according to the cause. 1. Cerumen impaction: Cerumen impaction is caused by the blockage of cerumen gland secretions in the ear canal, which can be manifested as unilateral tinnitus and hearing loss, etc. Symptoms will improve after the cerumen is removed from the ear canal. 2. Otitis media: It is an inflammatory disease caused by bacterial infection of the mucous membrane inside the middle ear drum, which can develop in one ear, manifesting symptoms such as ear stuffiness, tinnitus, hearing loss, ear pain, etc. Anti-infective drugs are needed to treat the symptoms. It requires symptomatic treatment with anti-infective drugs. 3. Neurogenic deafness: the specific cause is not obvious, may be related to the inner ear capillary spasm or embolism, viral infection. It can be manifested as sudden onset of hearing loss, which may be accompanied by tinnitus, ear stuffiness, dizziness and other symptoms. It requires symptomatic treatment with medicines that activate blood circulation, improve microcirculation, and nourish the nerves. Tinnitus with hearing loss, need to go to the otorhinolaryngology consultation, clear cause targeted treatment.