Timosartan optimal combination of drugs is to enhance the antihypertensive effect and prolong the duration of antihypertensive.
Clinically, Timosartan belongs to the angiotensin II receptor antagonist, after taking it can effectively block the vasoconstriction, sodium retention and remodeling effect of angiotensin II receptor, so as to play a role in lowering blood pressure. It is mainly used for the treatment of primary hypertension in adults. If patients with hypertension do not achieve the desired effect of lowering blood pressure after taking Timosartan alone, they need to combine with other antihypertensive drugs. Then it is necessary to combine with other antihypertensive drugs for treatment.
At present, the main recommended clinical combination of antihypertensive treatment program is mainly timosartan combined with dihydropyridine calcium channel blockers, such as amlodipine, felodipine extended-release tablets and so on. Secondly, it can also be combined with thiazide diuretics, such as hydrochlorothiazide. The combination of drugs can reduce the extracellular volume, reduce peripheral vascular resistance, reduce the extracellular calcium ions into the vascular smooth muscle cells, and reduce the vasoconstrictive response. This increases the effect of lowering blood pressure as well as prolonging the duration of lowering blood pressure.
Usually, after taking Timosartan, you may experience anemia, depression, bradycardia and other discomforts. At the same time, the drug is prohibited for people who are allergic to the components of the drug, people with severe impaired liver function, and liver and kidney function and blood pressure need to be monitored in the course of taking the drug. Pregnant and lactating women should use the drug under the supervision of a doctor.
If you need to take Timosartan in combination, it is recommended to consult a doctor in time to determine the specific medication and dosage of the drug and learn the precautions after a comprehensive assessment by the doctor.