What medicine to take for colds and fevers cannot be generalized, because the causes of colds and fevers should be found, for example, the most common causes of colds and fevers are bacterial, viral, mycoplasma, chlamydia and other pathogenic microbial infections, specific medications are as follows: 1. Viral infections: antiviral drugs or Chinese herbal medicine for evidence-based treatment. 2. The common ones are amoxicillin or amoxicillin clavulanic acid, or cephalosporins such as cefadroxil, cefuroxime, cefaclor, etc., or also macrolides such as azithromycin, erythromycin, roxithromycin, etc. If the adult is older than 18 years old, you can also use quinolone antibiotics, such as levofloxacin, moxifloxacin, etc. 3. Microbial infection caused by the cold, you can use macrolides or quinolones antibiotics for anti-infection treatment.