Before taking drugs should know its side effects, some drugs eaten will lead to insomnia, mainly the following: First, antidepressants, commonly used antidepressants such as Derexin, Promethazine, Fluoxetine, Paroxetine, Amphetamine, etc. can cause insomnia, with the role of regulating the excitability of the nervous system. Second, glucocorticoids, the application of glucocorticoids such as prednisone, methylprednisolone, dexamethasone, etc. can cause increased excitability of the nerves, resulting in insomnia. Third, diuretics, so that the number of urination increased, taking at night often due to increased urination and sleep, so diuretics should be taken during the day. Fourth, asthma drugs such as ephedrine, theophylline, etc. has a neuroleptic effect, sometimes patients take will occur agitation, insomnia and other symptoms. E. Taking eugenol produces insomnia, irritability, excessive sweating, trembling and other symptoms.