The severity of hyperbilirubinemia depends on how much higher the bilirubin is, and other liver tests, such as transaminases, albumin, cholinesterase, prothrombin activity, liver ultrasound, CT or MRI, blood tests, etc., as follows: 1, not serious: If all other tests are not significantly abnormal, and the bilirubin is only mildly elevated, the results are not serious, consider somatic jaundice, and can not be dealt with. 2, serious: some patients with significantly elevated bilirubin and one or more of the above mild to moderate abnormalities, to be combined with the test results to give a comprehensive assessment, if necessary, to give drug therapy. 3, other cases: in addition to liver factors caused by elevated bilirubin, there are hemolytic jaundice, obstructive jaundice, congenital deficiency of certain enzymes, as well as iron, copper metabolism abnormalities resulting in jaundice, to be based on the patient’s medical history, symptoms The severity of the condition should be assessed comprehensively based on the patient’s history, symptoms, signs, and ancillary examinations to try not to miss the diagnosis, but also to avoid overtreatment.