The blisters on the soles of the feet no quick treatment fast method, need to be based on the cause of the treatment; if caused by foot fungus, can be treated by oral antifungal drugs with topical antifungal drugs; if the foot eczema caused by the application of boric acid liquid wet compresses, with the topical glucocorticoid hormone ointment for local application. 1. Foot fungus: due to fungal infections, can be manifested as blisters on the soles of the feet, vesicles, itching and other symptoms. Under the guidance of a physician, oral itraconazole and other antifungal drugs, with topical terbinafine hydrochloride ointment or miconazole nitrate ointment for local application, it should be noted that foot fungus treatment time is longer, you should adhere to the treatment in order to prevent recurrence. 2. Foot eczema: due to allergies or contact with some physical and chemical factors, blisters, itching and other manifestations of the feet can occur. Boric acid solution can be applied to wet compresses, blisters can be used after drying mometasone furoate cream, tretinoin econazole cream, etc. to treat. Need to go to the hospital, a clear diagnosis of the cause of the targeted treatment, you can not just randomly use drugs.