Painkillers should not usually be taken for GI bleeding. Taking painkillers during gastrointestinal bleeding may lead to a situation where the bleeding worsens. Gastrointestinal bleeding is mainly to stop bleeding, patients can take oral omeprazole, ranitidine and other drugs to treat. If you need to use drugs, you need to use under the guidance of a doctor. During the period of gastrointestinal bleeding is not allowed to take painkillers, oral painkillers on the gastric mucosa caused by stimulation, may lead to bleeding aggravation and other situations. Gastrointestinal bleeding needs to go to the hospital immediately for treatment to stop bleeding. Excessive blood loss may lead to hemorrhagic shock, or even life-threatening. For gastrointestinal bleeding, medications such as omeprazole, ranitidine, famotidine or octreotide can be used to stop bleeding. Hemostasis can also be treated by endoscopic therapy, interventional therapy and surgery. It is recommended that patients go to the hospital in time, and if they need to use drugs, they should use them under the guidance of a doctor.