Pneumonia with azithromycin and cefadroxil which effect can not be generalized, need to be based on the pathogens that cause pneumonia and other decisions, should follow the doctor’s instructions for medication. 1. Azithromycin: effective against Streptococcus pneumoniae, Staphylococcus aureus, hemolytic streptococcus, Haemophilus influenzae, Chlamydia trachomatis, Mycoplasma pneumoniae and other pathogens. The adverse reactions of the drug are rash, abdominal pain, diarrhea, nausea, vomiting and so on. 2. Cefadroxil: It is effective against Neisseria spp, some Escherichia coli, Streptococcus chimericus, Salmonella, Shigella, Clostridium difficile, Weillonella, anaerobic gram-positive cocci, etc., and is ineffective against mycoplasma, chlamydia, and legionella and other special pathogens. Adverse reactions to this product include nausea, vomiting, diarrhea, and rash. Pneumonia can be caused by viruses, bacteria, Mycoplasma pneumoniae, fungi and other pathogenic infections, antibiotics are used for pneumonia caused by sensitive pathogens in order to achieve good results, so the choice of azithromycin or cefadroxil for pneumonia is good, need to be decided according to the specific conditions, depending on the individual, should be under the guidance of the doctor to use reasonable medication.