The condition of a rotten toe with pus is more likely to be a secondary disease, while the primary disease may be eczema or tinea pedis. First of all, anti-infective treatment is needed, through blood tests, as well as blood sedimentation, C-reactive protein, to observe whether the inflammation is in the acute stage. If it is in the acute stage, cefoxitin sodium injection or penicillin sodium injection should be administered immediately, and a topical solution of Ravnol should be applied twice a day for 20 minutes, followed by oxyfluoxacin gel for antibacterial and anti-infective treatment. For eczema, oral levocetirizine hydrochloride capsules and topical dextran ointment are needed. For tinea pedis, oral itraconazole capsules and topical terbinafine hydrochloride gel are needed for treatment.