In children with hepatitis, it is important to distinguish between acute hepatitis, such as hepatitis A, and chronic hepatitis, such as hepatitis B and hepatitis C. In acute hepatitis A, the patient may have nausea, vomiting, malaise, and yellowing of the skin and sclera. For acute hepatitis caused by hepatitis A, the patient will have nausea, some patients will have vomiting, fatigue, and yellowing of the skin and sclera. This is usually due to the presence of the hepatitis A virus in the food or water consumed by the patient, which causes an infection in the digestive tract, leading to the possibility of an outbreak of hepatitis A. The acute hepatitis A infection is self-limiting. Hepatitis A acute infection is a self-limiting disease, and the patient needs to be hospitalized for further hepatoprotective treatment and intravenous supportive therapy. Patients also need to rest more, after 1-2 months, the patient’s hepatitis A will be improved and cured. However, for chronic viral hepatitis B and chronic viral hepatitis C, the route is vertical transmission and blood transmission. If the patient has the possibility of hepatitis B and hepatitis C as mentioned above, he or she may also experience weakness, nausea, and vomiting. If the patient is in the window period of viral replication and liver function is severely impaired, yellowing of the skin and sclera may also occur. If the bilirubin is higher than 34.2 μmol/L, the patient needs to have further blood tests for hepatitis B DNA or hepatitis C RNA, and if the virus is replicating, combined with liver function impairment, antiviral treatment should be actively considered.