There is no such thing as the best combination program for lowering blood pressure, and different antihypertensive programs should be formulated according to the individual differences of patients and the combination of different diseases.
Single drug antihypertensive patients whose blood pressure still does not meet the standard generally consider a combination of drugs, according to the different mechanisms of hypertension drug selection, individual differences in patients and the combination of different diseases, so the choice of antihypertensive program needs to be formulated for the individual, such as the combination of renal insufficiency of hypertension patients can not use hydrochlorothiazide and other diuretics, there is no fixed best antihypertensive combination program.
There are five commonly used hypertension drugs, including diuretics, angiotensin-converting enzyme inhibitors (i.e., ACEIs), angiotensin receptor antagonists (i.e., ARBs), calcium antagonists (i.e., CCBs), and beta-blockers.
Commonly used combinations are CCBs in combination with ARBs or ACEIs, ACEIs or ARBs in combination with diuretics, CCBs in combination with diuretics, and CCBs in combination with beta-blockers. The purpose of the combination is so that the antihypertensive effects of the two blood pressure-lowering drugs can be synergistic and can counteract each other or mitigate adverse effects.
If the patient is diagnosed with hypertension, it is recommended to go to the hospital and follow the doctor’s instructions for antihypertensive treatment.