Transaminases are one of the important indicators in liver function tests, and elevated transaminases mostly represent impaired liver function. The key is to seek timely medical attention to clarify the specific causes of elevated transaminases for targeted treatment, and to pay attention to regulating lifestyle to avoid aggravating the burden on the liver. The first is to pay attention to rest, adjust work and rest, avoid exertion, stay up late, participate in physical exercise, and maintain the ideal weight. Second, in the diet to avoid spicy and stimulating salt and high oil, high fat food to avoid aggravating the liver burden, appropriate to eat more fresh fruits and vegetables, coarse grains of food, supplement quality protein, and at the same time to stop smoking and alcohol to reduce the burden on the liver. In addition, patients should avoid emotional excitement, keep a happy mood and have a positive and healthy mindset. Etiological treatment for patients with elevated transaminases is the key to lowering transaminases. If the aminotransferases are high due to non-pathological reasons such as fever, strenuous exercise, medication, alcohol consumption, etc., no special treatment is needed. If the aminotransferases are elevated due to hepatitis and other liver lesions, the patient should promptly improve the hepatitis virus series, liver ultrasound and other related laboratory tests and examinations, and adopt antiviral therapy and immunotherapy, as well as add liver protection therapy to promote liver function repair. To sum up, patients with high transaminases should consult a doctor in time to identify the cause of the disease and carry out corresponding treatment, and at the same time, they should do the above-mentioned life regulation to promote the repair of damage to the body.