Colds (i.e., acute upper respiratory tract infections) caused by children catching cold in their sleep at night can be caused by viral, bacterial, and other pathogen infections. Antiviral and antibiotic drugs can be used for treatment. 1. Viral infection: If there is no obvious fever, headache, muscle pain and other related symptoms, most of them are caused by the common cold, which is usually self-limiting in nature, and can be gradually recovered without treatment, only need to drink more water and pay attention to rest. However, if the child’s cold symptoms are more serious, accompanied by significant muscle pain, fatigue and other related symptoms, it may be influenza also need to use oseltamivir and other antiviral drugs treatment. 2. Bacterial infection: If your child has a significant fever, you need to be on the lookout for bacterial colds, which may require antibiotics such as amoxicillin. Note that the above drugs should be used under the guidance of a doctor, avoid unauthorized use of drugs, so as to avoid adverse effects. If a child’s symptoms are not relieved by the above medications, it is recommended to seek medical attention, complete the relevant examinations, identify the cause of the disease and target treatment.