There is no fastest and most effective treatment for knee pain. Generally, most of the causes of knee pain are caused by synovitis, knee osteoarthritis and so on. According to the cause of the disease, you can choose drugs, surgery and other ways of treatment. 1. Synovitis: Synovitis causes knee pain, mainly due to a variety of stimuli, such as trauma, local infection and other causes of a disease. After the synovitis NSAIDs can play the role of antipyretic, analgesic and anti-inflammatory drugs, patients can choose ibuprofen, diclofenac sodium, celecoxib and other treatments. If the use of medication is not effective, it may require arthroscopic synovectomy treatment. 2. Knee osteoarthritis: knee pain caused by knee osteoarthritis is mainly caused by chronic injury, inflammation of the knee joint leading to aging. Surgical treatments such as analgesics celecoxib, ibuprofen, and local injection of glucocorticoids can be used to relieve symptoms. Knee pain can also be caused by other reasons, such as trauma, etc. When using medication to treat the disease, it is recommended to consult a doctor and choose medication to treat the symptoms according to the doctor’s instructions and requirements.