The effect of metoprolol tartrate on blood glucose is generally not very significant. Metoprolol tartrate is a selective beta 1 receptor blocker used to treat hypertension, acute myocardial infarction, unstable angina, hypertrophic cardiomyopathy, and aortic coarctation. Metoprolol may interfere with glucose metabolism or mask symptoms of hypoglycemia, but it is relatively rare in the normal population and therefore has a less significant effect on blood glucose. However, diabetics need to be careful with its use to avoid hypoglycemia. Adverse effects of the drug mainly include: abdominal pain, nausea, vomiting, diarrhea, constipation, alopecia, thrombocytopenia, elevated aminotransferases, tinnitus, arthritis, and painful muscle spasms. Contraindications to the drug mainly include: cardiogenic shock, sick sinus node syndrome, atrioventricular block of the II or III degree, acute myocardial infarction, severe peripheral vascular disease, allergy to the components of the drug. It is recommended to use this drug in accordance with medical advice, especially diabetic patients need to consult a doctor in detail before use, so as not to lead to adverse consequences.