The availability of interferon antiviral therapy in the decompensated phase of hepatitis C cirrhosis is related to the grading criteria for quantitative assessment of liver reserve function. Liver functionchild classification is a grading scale commonly used in clinical practice to quantitatively assess liver reserve function in patients with cirrhosis. If the score is A, the patient must be treated with interferon. Currently, the preferred antiviral treatment for hepatitis C and its cirrhotic stage is DAAs, i.e., direct antiviral therapy, and the commonly used drugs are sofosbuvir, gecalcivir, and so on. If it is class B, patients can choose by themselves whether to use interferon antiviral therapy or not, if it is class C, interferon antiviral therapy is not needed The patient’s liver function compensation is a dynamic process, whether interferon antiviral treatment is needed is related to the patient’s condition. Interferon therapy is only one of the options available for hepatitis C. Patients should follow the doctor’s instructions for comprehensive treatment of hepatitis C.