Half of the sore throat and one ear pain is mainly caused by acute tonsillitis, purulent otitis media and acute pharyngitis, which can be treated with medication and surgery according to the cause. 1. Acute tonsillitis: When viruses and bacteria infect the tonsils, the pain in half of the throat can radiate to the ear and cause earache. Tonsillar inflammation is mainly treated by medication such as antiviral treatment (acyclovir) and antibiotic treatment (penicillin V, cephalosporin, etc.). 2. Suppurative otitis media: the accumulation of pus in the middle ear can cause unilateral sore throat and earache. The treatment of otitis media also mainly adopts medication, such as the application of glucocorticoids (dexamethasone) and antibiotics (penicillin), etc. If necessary, tympanotomy can be used to promote the drainage of pus in the cavity of the middle ear to alleviate the symptoms. 3. Acute pharyngitis: viral infection or stimulation by physical and chemical factors leads to acute inflammatory reaction of the mucous membrane and submucosa of the pharynx, resulting in pain in half of the throat and pain in one ear on the same side, which can be treated with Chinese medicines such as Blue Scutellaria Oral Liquid, Swelling Pain Capsule and Pu Dilan Anti-inflammatory Tablets. After the onset of the disease, we should actively seek medical advice to clarify the diagnosis, and follow the doctor’s instructions to standardize the use of medication and treatment.