Cephalosporin antibiotics are a class of antibiotics obtained by semi-synthesizing or changing the side chain of natural cephalosporin C as raw material. They are divided into five categories according to the age of invention. Commonly used injectable dosage forms include cefotaxime, ceftriaxone, ceftazidime, cefoperazone, etc.; oral varieties include cefixime and cefpodoxime ester. The three generations of cephalosporins have a wide antibacterial spectrum and have antibacterial effects on most Gram-negative bacilli. Ceftazidime and cefoperazone have powerful activities against Pseudomonas aeruginosa. Clinically, they are mainly used for serious infections caused by sensitive bacteria, such as the following respiratory tract infections, abdominal infections, pyelonephritis and complicated urinary tract infections, pelvic inflammatory diseases, bone and joint infections, complicated skin and soft tissue infections, and central nervous system infections.