The fastest way to solve the problem of not being able to poop is oral medication (polyethylene glycol bulk, mosapride), anal plug medication, enema treatment, surgical treatment, and so on. 1. Oral medication: commonly used laxatives are polyethylene glycol bulk, lactulose solution, etc.; commonly used gastrointestinal tract dynamics agents include mosapride, itopride, etc. 2. Enema treatment: saline or keserol enema can be chosen, which is suitable for patients with acute functional constipation. 3. Anal plug drugs: you can choose Keserol, glycerin suppositories and other drugs, which can lubricate the intestinal tract and promote defecation. 4. Surgical treatment: applicable to intestinal masses, intestinal obstruction and other diseases, simple drugs and enema treatment is not obvious. For the treatment of not being able to poop, it is recommended to consult a doctor for treatment, and take the medication as prescribed by the doctor.