A rheumatoid factor of 80 U/ml is an elevated condition and is usually serious. Increased rheumatoid factor can be seen in rheumatic immune diseases, but also in infectious diseases such as tuberculosis and chronic active hepatitis. Rheumatoid factor is a kind of autoantibody produced by denatured IgG stimulating the body, usually seen in rheumatoid arthritis, scleroderma, systemic lupus erythematosus and other autoimmune diseases, under normal circumstances, rheumatoid factor <20U/ml. if you suffer from rheumatism disease, rheumatoid factor 80U/ml usually belongs to the more serious situation. Rheumatoid factor 80U/ml can also be seen in infectious mononucleosis, infective endocarditis, tuberculosis, chronic active hepatitis and so on. It is recommended that patients with high rheumatoid factor should consult the Rheumatology and Immunology Department or other departments in a timely manner, complete the relevant examinations under the guidance of the doctor, and comply with the doctor's instructions in a timely manner after the diagnosis.