Commonly used medications for duodenal ulcers include drugs to inhibit gastric acid secretion such as omeprazole, drugs to protect the gastric mucosa such as bismuth potassium citrate, antibiotics such as amoxicillin, etc., but they are not specialized in treating duodenal ulcers. 1. Drugs to inhibit gastric acid secretion: proton pump inhibitors are the drugs of choice for the treatment of peptic ulcer, commonly used are omeprazole, lansoprazole, pantoprazole, etc., by inhibiting the activity of the proton pump, to achieve the effect of inhibiting gastric acid secretion. The healing rate of typical duodenal ulcer in 4 weeks is 90% to 100%. 2. Eradication of Helicobacter pylori drugs: Eradication of Helicobacter pylori can significantly reduce the recurrence rate of ulcers, the current common use of quadruple therapy, that is, a proton pump inhibitor (such as omeprazole, lansoprazole, etc.), a bismuth agent (such as bismuth potassium citrate, bismuth pectin, etc.), two antibiotics (such as amoxicillin, clindamycin, etc.). The standard course of treatment is 10 to 14 days. 3. Drugs for protecting gastric mucosa: bismuth, which presents colloidal form in acidic solution, can cover the surface of ulcer and block the damage of gastric mucosa by gastric acid, commonly used are bismuth potassium citrate, bismuth pectin, etc. Bismuth is mainly excreted by kidney, and can be used for the treatment of gastric ulcer. Bismuth is mainly excreted by the kidneys, and is contraindicated in people with renal dysfunction. The treatment of duodenal ulcer, there is no so-called “specialized” medicine. You should follow the doctor’s instructions to standardize the use of drugs, avoid self medication.