Saffron has the efficacy of activating blood circulation and removing blood stasis (promoting blood circulation and eliminating blood stasis in the body), cooling the blood and removing toxins (referring to the treatment of blood-heat and toxins), and relieving depression and tranquilizing the mind; it is used in the treatment of menstrual impediment (lumps in women’s lower abdomen), post-partum stasis, warm-heat poisonous spots (warm-heat poisonous evils invading the body leading to skin spots and plaques), melancholy, depression and palpitation and frenzy, and other diseases. Saffron is sweet in taste and flat in nature, it enters the liver meridian and blood division (in the four periods of warm disease, it belongs to the most in-depth stage or disease), it is good at activating blood circulation and removing blood stasis, promoting menstruation and eliminating crises, and it is strong and effective, therefore, it is often used in the clinic for dysmenorrhea caused by blood stasis, menstrual closure, menstrual irregularities, impure menstruation after childbirth, lumbar and abdominal pain, pain of abdominal mass and pain of injury of bruises and injuries. Saffron enters the liver meridian and blood division, not only activates blood stasis, but also cools blood and detoxifies, especially suitable for warm poisonous heat, body rash. It can be used alone to cool the blood and detoxify the toxin, or paired with Qing Ye and Ban Lan Gen to clear heat and detoxify the toxin (removing heat and toxin from the body). Measles heat and blood depression, measles not fast or rash is too dense, rash color dark and not fresh, often with comfrey, red peony and so on. Saffron enters the heart meridian, activates blood circulation and can disperse depression and open the knot, stabilizing the heart and mind. It can dispel depression, eliminate lumps and fullness, and stabilize the mind and spirit in cases of depression and unresolved, knotting up the chest and tightness of the qi, which may even lead to uneasiness of the mind and spirit, palpitation and trance, or madness, etc. It is also used in the treatment of anxiety and depression. If treating chest and diaphragm fullness caused by melancholy and depression, or panic and trance, use this drug alone in soup, or with Yu Jin. It should be used with caution in pregnant women. Before taking this medicine, it should be used under the guidance of a traditional Chinese medicine doctor, and should not be purchased and used on its own to avoid delaying the condition.